Pharmaceutical Laboratory

    Academic advisor
    Professor Du Hyung Choi Professor Du Hyung Choi
    Lab introduction The pharmaceutical laboratory is developing and evaluating various formulations based on QbD and researching process scale-up strategies.
    Major research area
    • QbD-based drug formulation design and process optimization research
    • Process research using mechanism-based model simulation
    • Process scale-up study using process analysis technology (PAT)
    Major achievement
    • Participation in international conferences and education
      • 2018 FREUND Seminar, Hamamatsu, Japan
      • 2018 ISPE Annual Meeting&Expo, Pennsylvania, PA, USA
      • 2018 EDEM Meeting, Edinburgh, UK
      • 2019 ISL-FD Conference, Ghent, Belgium
    • Major paper
      • 장*하 : Investigation of the effects of materials and dry granulation process on the mirabegron tablet by integrated QbD approach with multivariate analysis (Powder Technology, 2021)
      • 김*연 : Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design, (Pharmaceutics, 2021)
      • 박*서 : Application of mechanism-based modeling to predict drug quality during the pharmaceutical unit operations of granulation and compression: A review, (Journal of Pharmaceutical Investigation, 2020)
      • 장*하 : Model-Based Scale-up Methodologies for Pharmaceutical Granulation, (Pharmaceutics, 2020)
      • 염*빈 : Application of the discrete element method for manufacturing process simulation in the pharmaceutical industry, (Pharmaceutics, 2019)
      • 염*빈 : Scale-up strategy in quality by design approach for pharmaceutical blending process with discrete element method simulation, (Pharmaceutics, 2019)
      • 이*빈 : Orally disintegrating films focusing on formulation, manufacturing process, and characterization, (Journal of Pharmaceutical Investigation, 2017)
      • 이*빈 : Formulation optimization and in vitro characterization of orally disintegrating films using a factorial design and mathematical modeling for drug release (Chemical and Pharmaceutical Bulletion, 2016)
    Contact
    • Tel: 055-320-3395
    • E-mail: choidh@inje.ac.kr