Lab introduction |
The Molecular Biotechnology Lab searches for new food and drug materials with anti-cancer, anti-inflammatory, anti-atopic, antioxidant, antibacterial, anti-obesity, anti-diabetic, and immunomodulatory properties from natural plant and microbial resources, and identifies the delivery mechanism.
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Major achievement |
- Major paper: About 30 SCI grades, about 40 listings
- Orostachys japonicus ethyl acetate fraction suppresses MRSA biofilm formation. Jae-Hyeon Kim, Su-Yeon Han, Ji-Hye Kwon,Dong-Seok Lee. Asian Pacific Journal of Tropical Medicine 13(1): 38-45, 2020.
- Anticancer effect of the ethyl acetate fraction from Orostachys japonicus on MDA-MB-231 human breast cancer cells through extensive induction of apoptosis, cell cycle arrest, and antimetastasis. Ji-Hye Kwon, Jae-Hyeon Kim, Deok-Seon Ryu, Hyun-Ji Lee, Dong-Seok Lee. Evidence-Based Complementary and Alternative Medicine Article ID 8951510, 2019.
- Orostachys japonicus exerts antipancreatic cancer activity through induction of apoptosis and cell cycle arrest in PANC‐1 cells. Ji-Hyun Kim, Gi-Suk Nam, Sung-Hyun Kim, Deok-Seon Ryu, Dong-Seok Lee. Food Science and Nutrition 7: 3549–3559, 2019.
- Anti-cancer effect of ethylacetate fraction from Orostachys japonicus on HT-29 human colon cancer cells by induction of apoptosis through caspase-dependent signaling pathway. Deok-Seon Ryu, Hyun-Ji Lee, Ji-Hye Kwon, Dong-Seok Lee. Asian Pacific Journal of Tropical Medicine 11(5): 330-335, 2018.
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